Isotopic enrichment is often required for a more efficient characterization by solid-state NMR of porous solids (mesoporous silicas, zeolites, Metal-Organic Frameworks (MOFs), etc) containing NMR-active elements of low natural abundance. Precursors enriched with stable isotopes (¹⁷O, ²⁹Si, etc) can be used during the material synthesis. This labeling strategy boosts the sensitivity and selectivity of the NMR measurements, offering new information about the structure, active sites, formation mechanism, dynamics and properties of these solids.

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